Linkage analysis using restriction fragment length polymorphisms
نویسندگان
چکیده
منابع مشابه
Man Using Restriction Fragment Length Polymorphisms
We describe a new basis for the construction of a genetic linkage map of the human genome. The basic principle of the mapping scheme is to develop, by recombinant DNA techniques, random single-copy DNA probes capable of detecting DNA sequence polymorphisms, when hybridized to restriction digests of an individual's DNA. Each of these probes will define a locus. Loci can be expanded or contracted...
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We describe a new basis for the construction of a genetic linkage map of the human genome. The basic principle of the mapping scheme is to develop, by recombinant DNA techniques, random single-copy DNA probes capable of detecting DNA sequence polymorphisms, when hybridized to restriction digests of an individual's DNA. Each of these probes will define a locus. Loci can be expanded or contracted...
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ژورنال
عنوان ژورنال: Animal blood-group research information
سال: 1990
ISSN: 1884-3867
DOI: 10.5924/abgri1983.1990.9